Compare filtered data to raw reads
Let's take a closer look at the difference the read filtering makes. Here is a plot with three different coverage tracks. From top to bottom they show total coverage, coverage from high-quality alignments, and coverage from low-quality alignments.
Examine the plot above. Which of the following statements accurately describe the depicted coverage data?
- Most read alignments were of high quality.
- The most pronounced peaks are due to low-quality alignments.
- There are peaks in the high-quality coverage profile.
This exercise is part of the course
ChIP-seq with Bioconductor in R
Hands-on interactive exercise
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