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Compare filtered data to raw reads

Let's take a closer look at the difference the read filtering makes. Here is a plot with three different coverage tracks. From top to bottom they show total coverage, coverage from high-quality alignments, and coverage from low-quality alignments.

Examine the plot above. Which of the following statements accurately describe the depicted coverage data?

  1. Most read alignments were of high quality.
  2. The most pronounced peaks are due to low-quality alignments.
  3. There are peaks in the high-quality coverage profile.

This exercise is part of the course

ChIP-seq with Bioconductor in R

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