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Exercise

MA plot

An MA plot visualizes differences between two groups relative to average signal intensity. This is useful to assess potential biases in the data. Typically, most peak intensities aren't expected to change between conditions. This means points in the plot should be grouped around a horizontal line at 0, corresponding to no change. MA plots are also useful to get a quick visual impression of how large the differences between groups are.

Like the plotting functions you used earlier, DiffBind provides a function, dba.plotMA(), to create MA plots that can extract all necessary information from the DBA object.

Instructions

100 XP
  • Use the dba.plotMA() function to create an MA plot.
  • Take a look at the plot. Note how significant differences are highlighted.