1. Learn
    2. /
  2. Courses
    3. /
  3. Differential Expression Analysis with limma in R

Exercise

Volcano plot

Next, you will create a volcano plot to visualize the extent of differential expression in the leukemia study, which displays the log odds of differential expression on the y-axis versus the log fold change on the x-axis.

Instructions

100 XP

The fitted model object of the leukemia study from Chapter 2, fit2, has been loaded in your workspace. The limma package is already loaded.

  • Create a volcano plot that highlights the top 5 genes.

  • Label the top 5 genes with their gene symbols by passing the column symbol of the data frame fit2$genes to the argument names.