Exercise

Design matrix

The doxorubicin experiment is a 2x2 factorial design, so you will need to create a combined variable to use in the group-means parametrization.

Instructions

100 XP

The ExpressionSet object eset with the doxorubicin data has been loaded in your workspace.

Combine the variables genotype (WT vs. Top2b null) and treatment (PBS vs. Dox) into a single factor variable.
Use model.matrix to create a design matrix with no intercept.

Take Hint (-30 XP)