Significance

What is the difference between a statistically significant effect and a clinically (or "substantively") significant effect?

50 XP

Statistically significant effects are bigger than clinically significant effects.
Statistically significant effects don't necessarily matter, whereas clinically significant effects do matter.
Statistically significant effects have smaller confidence intervals than clinically significant effects.
Statistically significant effects always matter, whereas clinically significant effects sometimes don't matter.